Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat

Jie Li; Jianhuan Li; Wei Xiang; Hui Xu; Bolong Lv; Qing Wu

doi:doi:10.11648/j.sd.20190704.19

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Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat

Jie Li, Jianhuan Li, Wei Xiang, Hui Xu, Bolong Lv, Qing Wu

Published in Science Discovery (Volume 7, Issue 4)

Received: 25 June 2019 Published: 27 August 2019

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Abstract

Aquatic animals are susceptible to N-dimethylnitrosamine pollution in water quality or feed, which is a non-negligible problem in food safety detection. Gas chromatography/triple four-stage mass spectrometry combined with QuEChERS was used to detect N-dimethylnitrosamine in duck and poultry meat, and acetonitrile, salting-out agent and purifying agent were used to extract duck and poultry meat samples. The results of detection and analysis showed that the results were good. The standard curve was highly correlated in the range of 5ng/mL to 1000ng/mL (R² > 0.9997). The recovery of standard sample was 82.51%-115.42%, RSD was 1.89-2.99, instrument detection limit was 4.4ng/mL and method detection limit was 0.44ng/g after adding standard sample and matrix effect treatment. The results showed that the recovery of standard sample was 82.51%-115.42%, RSD was 1.89-2.99, and instrument detection limit was 4 ng/mL. Other methods can reduce the operation steps and improve the detection accuracy.

Published in	Science Discovery (Volume 7, Issue 4)
DOI	10.11648/j.sd.20190704.19
Page(s)	227-231
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

N-Nitrosodimethylamine,Tiple Quadrupole Mass Spectrometer, QuEChERS, Duck Meat Products

References

[1]	闾春林，刘永东，王云海，钟儒刚.二甲胺与亚硝酸反应生成N,N-二甲基亚硝胺的理论研究. 化学学报，2007, 65(16);1568～1572。
[2]	中华人民共和国国家卫生和计划生育委员会、国家食品药品监督管理总局.食品安全国家标准食品中污染物限量, GB2762-2017, 2017-03-17发布2017-09-17实施。
[3]	闾春林，刘永东，王云海，钟儒刚.二甲胺与亚硝酸反应生成N,N-二甲基亚硝胺的理论研究. 化学学报,2007, 65(16); 1568-1572。
[4]	谈超群，钟毅杰，黄华. 二甲基亚硝胺消毒副产物的生成途径及其控制方法研究进展. 安全与环境学报,2017, 17(6); 2292-2300。
[5]	An, D., Chen, Y.N., Gu, B., Westerhoff, P., Hanigan, D., Herckes P., and et al. Lower molecular weight fractions of PolyDADMAC coagulants disproportionately contribute to N-nitrosodimethylamine formation during water treatment. Water Research, 2019, 150; 466-472.
[6]	张凤艳，蒋万枫，王蓓，高嵩，桑迎迎，田玲. 水产品中N-二甲基亚硝胺气相色谱-串联质谱测定样品处理方法的改进. 中国卫生检验杂志, 2018,28 (11) ;1306-1317。
[7]	Hinneh, K.D.C., Hanafi, A.E., He, K., Kosak, K., Echigo, S.Y., Asada, Y.h., Itoh, S.H. Formation of N-nitrosodimethylamine by chloramination of anthropogenic nitrogenous compounds with dimethylamine monitored by Japanese water authorities. Journal of Hazardous Materials, 2019, 367; 620–628.
[8]	Sgroia, M., Vagliasindia, F.G.A., Snyder, S.A., Roccaro, P. N-Nitrosodimethylamine (NDMA) and its precursors in water andwastewater: A review on formation and removal. Chemosphere, 2018,,191; 685-703.
[9]	Zhang, Q.X., Jin, L., Zhang, F., Yao, K., Ren, Y., Zhang, J.Q., Zhang, Q.H., He, Q., Wan, Y.P., Chi, Y.L. Analysis of 7 volatileN-nitrosamines in Chinese Sichuan salted vegetablesby gas chromatography-tandem mass spectrometry coupled to modified QuEchERS extraction Food Control, 2019, 98;342–347.
[10]	周佳，孙嘉茵，李宇茜，唐维英，徐小平. GC-MS/MS 同位素内标法测定肉制品中N-二甲基亚硝胺. 中国测试, 2016,42(9);46-49。
[11]	冯秀娟，龚慧，张学玲. GC-MS 法测定食品中N- 二甲基亚硝胺含量. 中外食品工业, 2015;43-46。
[12]	乔玲，纪晗旭，宋佳，李榕，胡飞杰. 肉制品中N-二甲基亚硝胺的测定. 现代食品, 2018, 1;103-105。
[13]	冯秀娟，马桂娟，王紫昕，张文轩，张瑶. 肉制品中N-二甲基亚硝胺测定及不确定度评定. 食品研究与开发, 2017, 38(6);153-159。
[14]	Hu, S.P., Zhao, M., Mao, Q.Q., Fang, C.Y., Chen, D.W., Yan, P.C. Rapid one-step cleanup method to minimize matrix effects for residue analysis of alkaline pesticides in tea using liquid chromatography-high resolution mass spectrometry. Food Chemistry, 2019, Accepted Manuscript, DOI: https://doi.org/10.1016/j.foodchem.2019.125146.
[15]	Palma, C., Morgado, V., Bettencourt da Silva, R.J.N. Top-down evaluation of matrix effects uncertainty. Talanta, 2019, 192; 278-287.

Cite This Article

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APA Style

Jie Li, Jianhuan Li, Wei Xiang, Hui Xu, Bolong Lv, et al. (2019). Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat. Science Discovery, 7(4), 227-231. https://doi.org/10.11648/j.sd.20190704.19

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ACS Style

Jie Li; Jianhuan Li; Wei Xiang; Hui Xu; Bolong Lv, et al. Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat. Sci. Discov. 2019, 7(4), 227-231. doi: 10.11648/j.sd.20190704.19

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AMA Style

Jie Li, Jianhuan Li, Wei Xiang, Hui Xu, Bolong Lv, et al. Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat. Sci Discov. 2019;7(4):227-231. doi: 10.11648/j.sd.20190704.19

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@article{10.11648/j.sd.20190704.19,
  author = {Jie Li and Jianhuan Li and Wei Xiang and Hui Xu and Bolong Lv and Qing Wu},
  title = {Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat},
  journal = {Science Discovery},
  volume = {7},
  number = {4},
  pages = {227-231},
  doi = {10.11648/j.sd.20190704.19},
  url = {https://doi.org/10.11648/j.sd.20190704.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20190704.19},
  abstract = {Aquatic animals are susceptible to N-dimethylnitrosamine pollution in water quality or feed, which is a non-negligible problem in food safety detection. Gas chromatography/triple four-stage mass spectrometry combined with QuEChERS was used to detect N-dimethylnitrosamine in duck and poultry meat, and acetonitrile, salting-out agent and purifying agent were used to extract duck and poultry meat samples. The results of detection and analysis showed that the results were good. The standard curve was highly correlated in the range of 5ng/mL to 1000ng/mL (R2 > 0.9997). The recovery of standard sample was 82.51%-115.42%, RSD was 1.89-2.99, instrument detection limit was 4.4ng/mL and method detection limit was 0.44ng/g after adding standard sample and matrix effect treatment. The results showed that the recovery of standard sample was 82.51%-115.42%, RSD was 1.89-2.99, and instrument detection limit was 4 ng/mL. Other methods can reduce the operation steps and improve the detection accuracy.},
 year = {2019}
}

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TY  - JOUR
T1  - Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat
AU  - Jie Li
AU  - Jianhuan Li
AU  - Wei Xiang
AU  - Hui Xu
AU  - Bolong Lv
AU  - Qing Wu
Y1  - 2019/08/27
PY  - 2019
N1  - https://doi.org/10.11648/j.sd.20190704.19
DO  - 10.11648/j.sd.20190704.19
T2  - Science Discovery
JF  - Science Discovery
JO  - Science Discovery
SP  - 227
EP  - 231
PB  - Science Publishing Group
SN  - 2331-0650
UR  - https://doi.org/10.11648/j.sd.20190704.19
AB  - Aquatic animals are susceptible to N-dimethylnitrosamine pollution in water quality or feed, which is a non-negligible problem in food safety detection. Gas chromatography/triple four-stage mass spectrometry combined with QuEChERS was used to detect N-dimethylnitrosamine in duck and poultry meat, and acetonitrile, salting-out agent and purifying agent were used to extract duck and poultry meat samples. The results of detection and analysis showed that the results were good. The standard curve was highly correlated in the range of 5ng/mL to 1000ng/mL (R2 > 0.9997). The recovery of standard sample was 82.51%-115.42%, RSD was 1.89-2.99, instrument detection limit was 4.4ng/mL and method detection limit was 0.44ng/g after adding standard sample and matrix effect treatment. The results showed that the recovery of standard sample was 82.51%-115.42%, RSD was 1.89-2.99, and instrument detection limit was 4 ng/mL. Other methods can reduce the operation steps and improve the detection accuracy.
VL  - 7
IS  - 4
ER  -

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Author Information

Jie Li

Anhui Topway Testing Service Co., Ltd., Xuancheng, China
Jianhuan Li

Anhui Topway Testing Service Co., Ltd., Xuancheng, China
Wei Xiang

Anhui Topway Testing Service Co., Ltd., Xuancheng, China
Hui Xu

Anhui Topway Testing Service Co., Ltd., Xuancheng, China
Bolong Lv

Anhui Topway Testing Service Co., Ltd., Xuancheng, China
Qing Wu

Anhui Topway Testing Service Co., Ltd., Xuancheng, China

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Sections

Plain Text BibTeX RIS

APA Style

Jie Li, Jianhuan Li, Wei Xiang, Hui Xu, Bolong Lv, et al. (2019). Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat. Science Discovery, 7(4), 227-231. https://doi.org/10.11648/j.sd.20190704.19

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ACS Style

Jie Li; Jianhuan Li; Wei Xiang; Hui Xu; Bolong Lv, et al. Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat. Sci. Discov. 2019, 7(4), 227-231. doi: 10.11648/j.sd.20190704.19

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AMA Style

Jie Li, Jianhuan Li, Wei Xiang, Hui Xu, Bolong Lv, et al. Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat. Sci Discov. 2019;7(4):227-231. doi: 10.11648/j.sd.20190704.19

Copy | Download

@article{10.11648/j.sd.20190704.19,
  author = {Jie Li and Jianhuan Li and Wei Xiang and Hui Xu and Bolong Lv and Qing Wu},
  title = {Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat},
  journal = {Science Discovery},
  volume = {7},
  number = {4},
  pages = {227-231},
  doi = {10.11648/j.sd.20190704.19},
  url = {https://doi.org/10.11648/j.sd.20190704.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20190704.19},
  abstract = {Aquatic animals are susceptible to N-dimethylnitrosamine pollution in water quality or feed, which is a non-negligible problem in food safety detection. Gas chromatography/triple four-stage mass spectrometry combined with QuEChERS was used to detect N-dimethylnitrosamine in duck and poultry meat, and acetonitrile, salting-out agent and purifying agent were used to extract duck and poultry meat samples. The results of detection and analysis showed that the results were good. The standard curve was highly correlated in the range of 5ng/mL to 1000ng/mL (R2 > 0.9997). The recovery of standard sample was 82.51%-115.42%, RSD was 1.89-2.99, instrument detection limit was 4.4ng/mL and method detection limit was 0.44ng/g after adding standard sample and matrix effect treatment. The results showed that the recovery of standard sample was 82.51%-115.42%, RSD was 1.89-2.99, and instrument detection limit was 4 ng/mL. Other methods can reduce the operation steps and improve the detection accuracy.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Study on Rapid Detection of N-Nitrosodimethylamine in Duck and Poultry Meat
AU  - Jie Li
AU  - Jianhuan Li
AU  - Wei Xiang
AU  - Hui Xu
AU  - Bolong Lv
AU  - Qing Wu
Y1  - 2019/08/27
PY  - 2019
N1  - https://doi.org/10.11648/j.sd.20190704.19
DO  - 10.11648/j.sd.20190704.19
T2  - Science Discovery
JF  - Science Discovery
JO  - Science Discovery
SP  - 227
EP  - 231
PB  - Science Publishing Group
SN  - 2331-0650
UR  - https://doi.org/10.11648/j.sd.20190704.19
AB  - Aquatic animals are susceptible to N-dimethylnitrosamine pollution in water quality or feed, which is a non-negligible problem in food safety detection. Gas chromatography/triple four-stage mass spectrometry combined with QuEChERS was used to detect N-dimethylnitrosamine in duck and poultry meat, and acetonitrile, salting-out agent and purifying agent were used to extract duck and poultry meat samples. The results of detection and analysis showed that the results were good. The standard curve was highly correlated in the range of 5ng/mL to 1000ng/mL (R2 > 0.9997). The recovery of standard sample was 82.51%-115.42%, RSD was 1.89-2.99, instrument detection limit was 4.4ng/mL and method detection limit was 0.44ng/g after adding standard sample and matrix effect treatment. The results showed that the recovery of standard sample was 82.51%-115.42%, RSD was 1.89-2.99, and instrument detection limit was 4 ng/mL. Other methods can reduce the operation steps and improve the detection accuracy.
VL  - 7
IS  - 4
ER  -

Copy | Download