An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus G<sub>II</sub> Infection in a University

Yapin Li; Huisuo Yang; Haiyang Zhang; Min Wang; Qingfeng Li; Jian Wang; Wenjing Song; Dongqi Gao

doi:doi:10.11648/j.sd.20190702.13

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An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus G_II Infection in a University

Yapin Li, Huisuo Yang, Haiyang Zhang, Min Wang, Qingfeng Li, Jian Wang, Wenjing Song, Dongqi Gao

Published in Science Discovery (Volume 7, Issue 2)

Received: 19 January 2019 Published: 23 May 2019

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Abstract

Objective: To investigate an acute gastroenteritis epidemic in a university and to identify the scale, to find the possible causes of the outbreak. Methods: The field epidemiological survey method was used for information collection. Case-control and retrospective cohort study methods were used. The database was established with SPSS 25.0 and statistical analysis was performed. Results: In January 2018, an outbreak of acute gastroenteritis occurred in a university. A total of 162 cases were found and the attack rate was 8.94% (162/1813), all of whom were students. All the cases were eaten in the same student canteen. Case-control studies showed that on January 10th, lunch braised pork ribs, 10th dinner tomato scrambled eggs, and 11th dinner cakes were suspicious food. Norovirus nucleic acid was detected in the anal swab and fecal specimens of the case and canteen staff, all of which were GII type. The investigation found that there was no hand washing facility in the student canteen. The staff in the canteen did not wear masks, hats and gloves in the operation. The kitchen had no tableware disinfection cabinet, and the canteen detected 4 cases of Norovirus nucleic acid positive. Conclusions: This epidemic was an outbreak of acute gastroenteritis caused by Norovirus GII infection in a university. It is recommended to strengthen the management of food workers, strictly check the medical examination before taking up the post, strictly apply the fake sales system, and regularly check the personnel who have symptoms related to the gastrointestinal tract. Purchase food cabinet disinfection cabinets, disinfect food utensils in strict accordance with the operating procedures; add hand washing facilities in the cafeteria; change the table meal method into a meal method. Conduct health education for students and develop good health habits.

Published in	Science Discovery (Volume 7, Issue 2)
DOI	10.11648/j.sd.20190702.13
Page(s)	72-77
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Norovirus, Outbreak, Investigation

References

[1]	诺如病毒感染暴发调查和预防控制技术指南（2015版），传染病专报，2015,3（37）：1-44。
[2]	连怡遥，骆洪梅，冉陆等。中国2014_2018年学校和托幼机构诺如病毒疫情流行病学分析，中国学校卫生，2019，40（3）：406-410。
[3]	蔡秀芝，徐洪娜，潘玉辉等。哈尔滨市2017 年诺如病毒感染暴发调查，中国公共卫生管理，2018，34（5）：712-714。
[4]	栾明春，刘颖丽，郎兴莹等。大连地区食源性腹泻病例中诺如病毒基因特征分析，中国微生态学杂志，2018，30（11）：1313-1316。
[5]	戴映雪，速丽媛，刘云升等。成都市2017 年诺如病毒聚集性疫情及影响因素分析。中国学校卫生，2019，40（1）：107-109。
[6]	曹小萍，丁致远，魏崇崇等。无锡市一起诺如病毒急性胃肠炎暴发疫情调查分析，世界最新医学信息文摘，2018，18（92）：284-286。
[7]	方玉莲，王维，王萍等。天津地区急性胃肠炎患儿诺如病毒分子流行病学分析，2019，21（2）：139-143。
[8]	马涛，张敏，洪镭等。南京市某小学一起GII.P7 - GII.6 型诺如病毒引起的急性胃肠炎暴发调查，现代预防医学，2018，45（22）：4188-4191。
[9]	桑向来。甘肃省食源性诺如病毒流行特征及影响因素分析，现代预防医学，2018，45（24）：4423-4426。
[10]	陈波，翁正军，陈莫娇等。学校感染性腹泻疫情中诺如病毒的分子流行病学分析，中国卫生卫生检验杂志，2019，29（2）：174-176。
[11]	陈灿1，王虹玲2，严剑等。舟山市一起诺如病毒暴发疫情的病原学鉴定及基因特征分析，现代预防医学，2018，4（17）：3173-3177。
[12]	乔凤娟，孙炳欣，孙宇等。一起大学校园内由诺如病毒GⅡ型引起急性胃肠道疫情的病原分子生物学特征分析，中国卫生检验杂志，2018，28（17）：2107-2109。
[13]	倪朝荣，吕斌，刘铁诚等。一起波及4所学校的诺如病毒胃肠炎暴发疫情调查，预防医学，2019，31（3）：305-308。
[14]	阳文新，时惠东，姚露等。某部聚集性诺如病毒感染的预防及治疗措施，2019，21（1）：87-88。
[15]	Mesquita JR, Barclay L, Nascimento MS & Vinje J. Novel norovirus in dogs with diarrhea. Emerg Infect Dis 2010, 16: 980-2.
[16]	Zheng DP, et al. Norovirus classification and proposed strain nomenclature. Virology 2006, 346: 312-23.
[17]	Lopman B, Vennema H, Kohli E, et al. Increase in viral gastroenteritis outbreaks in Europe and epidemic spread of new norovirus variant [J]. Lancet, 2004, 363 (9410): 682-688.
[18]	Kirby AE, Shi J, Montes J, Lichtenstein M, Moe CL.Disease course and viral shedding in experimental Norwalk virus and Snow Mountain virus infection. J Med Virol. 2014 Dec; 86 (12): 2055-64. doi: 10.1002/jmv.23905. Epub 2014 Feb 14.
[19]	Teunis PF1, Sukhrie FH2, Vennema H2, Bogerman J3, Beersma MF3, Koopmans MP3. Shedding of norovirus in symptomatic and asymptomatic infections.Epidemiol Infect. 2015 Jun;143 (8): 1710-7. doi: 0.1017/S095026881400274X. Epub 2014 Oct 22.
[20]	Aoki Y, Suto A, Mizuta K, Ahiko T, Osaka K, Matsuzaki Y. Duration of norovirus excretion and the longitudinal course of viral load in norovirus-infected elderly patients.J Hosp Infect. 2010 May; 75 (1): 42-6.
[21]	Frange P, Touzot F, Debre M, et al. Prevalence and clinical impact of norovirus fecal shedding in children with inherited immune deficiencies. The Journal of infectious diseases 2012, 206 (8): 1269-74.
[22]	Jeong AY, Jeong HS, Lee JS, et al. Occurrence of norovirus infections in asymptomatic food handlers in South Korea. Journal of clinical microbiology 2013, 51 (2): 598-600.
[23]	Yu JH, Kim NY, Lee EJ, Jeon IS. Norovirus infections in asymptomatic food handlers in elementary schools without norovirus outbreaks in some regions of Incheon, Korea. Journal of Korean medical science 2011, 26 (6): 734-9.

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APA Style

Yapin Li, Huisuo Yang, Haiyang Zhang, Min Wang, Qingfeng Li, et al. (2019). An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus GII Infection in a University. Science Discovery, 7(2), 72-77. https://doi.org/10.11648/j.sd.20190702.13

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ACS Style

Yapin Li; Huisuo Yang; Haiyang Zhang; Min Wang; Qingfeng Li, et al. An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus GII Infection in a University. Sci. Discov. 2019, 7(2), 72-77. doi: 10.11648/j.sd.20190702.13

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AMA Style

Yapin Li, Huisuo Yang, Haiyang Zhang, Min Wang, Qingfeng Li, et al. An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus GII Infection in a University. Sci Discov. 2019;7(2):72-77. doi: 10.11648/j.sd.20190702.13

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@article{10.11648/j.sd.20190702.13,
  author = {Yapin Li and Huisuo Yang and Haiyang Zhang and Min Wang and Qingfeng Li and Jian Wang and Wenjing Song and Dongqi Gao},
  title = {An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus GII Infection in a University},
  journal = {Science Discovery},
  volume = {7},
  number = {2},
  pages = {72-77},
  doi = {10.11648/j.sd.20190702.13},
  url = {https://doi.org/10.11648/j.sd.20190702.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20190702.13},
  abstract = {Objective: To investigate an acute gastroenteritis epidemic in a university and to identify the scale, to find the possible causes of the outbreak. Methods: The field epidemiological survey method was used for information collection. Case-control and retrospective cohort study methods were used. The database was established with SPSS 25.0 and statistical analysis was performed. Results: In January 2018, an outbreak of acute gastroenteritis occurred in a university. A total of 162 cases were found and the attack rate was 8.94% (162/1813), all of whom were students. All the cases were eaten in the same student canteen. Case-control studies showed that on January 10th, lunch braised pork ribs, 10th dinner tomato scrambled eggs, and 11th dinner cakes were suspicious food. Norovirus nucleic acid was detected in the anal swab and fecal specimens of the case and canteen staff, all of which were GII type. The investigation found that there was no hand washing facility in the student canteen. The staff in the canteen did not wear masks, hats and gloves in the operation. The kitchen had no tableware disinfection cabinet, and the canteen detected 4 cases of Norovirus nucleic acid positive. Conclusions: This epidemic was an outbreak of acute gastroenteritis caused by Norovirus GII infection in a university. It is recommended to strengthen the management of food workers, strictly check the medical examination before taking up the post, strictly apply the fake sales system, and regularly check the personnel who have symptoms related to the gastrointestinal tract. Purchase food cabinet disinfection cabinets, disinfect food utensils in strict accordance with the operating procedures; add hand washing facilities in the cafeteria; change the table meal method into a meal method. Conduct health education for students and develop good health habits.},
 year = {2019}
}

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TY - JOUR
T1 - An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus GII Infection in a University
AU - Yapin Li
AU - Huisuo Yang
AU - Haiyang Zhang
AU - Min Wang
AU - Qingfeng Li
AU - Jian Wang
AU - Wenjing Song
AU - Dongqi Gao
Y1 - 2019/05/23
PY - 2019
N1 - https://doi.org/10.11648/j.sd.20190702.13
DO - 10.11648/j.sd.20190702.13
T2 - Science Discovery
JF - Science Discovery
JO - Science Discovery
SP - 72
EP - 77
PB - Science Publishing Group
SN - 2331-0650
UR - https://doi.org/10.11648/j.sd.20190702.13
AB - Objective: To investigate an acute gastroenteritis epidemic in a university and to identify the scale, to find the possible causes of the outbreak. Methods: The field epidemiological survey method was used for information collection. Case-control and retrospective cohort study methods were used. The database was established with SPSS 25.0 and statistical analysis was performed. Results: In January 2018, an outbreak of acute gastroenteritis occurred in a university. A total of 162 cases were found and the attack rate was 8.94% (162/1813), all of whom were students. All the cases were eaten in the same student canteen. Case-control studies showed that on January 10th, lunch braised pork ribs, 10th dinner tomato scrambled eggs, and 11th dinner cakes were suspicious food. Norovirus nucleic acid was detected in the anal swab and fecal specimens of the case and canteen staff, all of which were GII type. The investigation found that there was no hand washing facility in the student canteen. The staff in the canteen did not wear masks, hats and gloves in the operation. The kitchen had no tableware disinfection cabinet, and the canteen detected 4 cases of Norovirus nucleic acid positive. Conclusions: This epidemic was an outbreak of acute gastroenteritis caused by Norovirus GII infection in a university. It is recommended to strengthen the management of food workers, strictly check the medical examination before taking up the post, strictly apply the fake sales system, and regularly check the personnel who have symptoms related to the gastrointestinal tract. Purchase food cabinet disinfection cabinets, disinfect food utensils in strict accordance with the operating procedures; add hand washing facilities in the cafeteria; change the table meal method into a meal method. Conduct health education for students and develop good health habits.
VL - 7
IS - 2
ER -

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Author Information

Yapin Li

Center for Disease Control and Prevention of Central Theater, Beijing, China
Huisuo Yang

Center for Disease Control and Prevention of Central Theater, Beijing, China
Haiyang Zhang

Center for Disease Control and Prevention of Central Theater, Beijing, China
Min Wang

Center for Disease Control and Prevention of Central Theater, Beijing, China
Qingfeng Li

Center for Disease Control and Prevention of Central Theater, Beijing, China
Jian Wang

Center for Disease Control and Prevention of Central Theater, Beijing, China
Wenjing Song

Center for Disease Control and Prevention of Central Theater, Beijing, China
Dongqi Gao

Center for Disease Control and Prevention of Central Theater, Beijing, China

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APA Style

Yapin Li, Huisuo Yang, Haiyang Zhang, Min Wang, Qingfeng Li, et al. (2019). An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus GII Infection in a University. Science Discovery, 7(2), 72-77. https://doi.org/10.11648/j.sd.20190702.13

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ACS Style

Yapin Li; Huisuo Yang; Haiyang Zhang; Min Wang; Qingfeng Li, et al. An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus GII Infection in a University. Sci. Discov. 2019, 7(2), 72-77. doi: 10.11648/j.sd.20190702.13

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AMA Style

Yapin Li, Huisuo Yang, Haiyang Zhang, Min Wang, Qingfeng Li, et al. An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus GII Infection in a University. Sci Discov. 2019;7(2):72-77. doi: 10.11648/j.sd.20190702.13

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@article{10.11648/j.sd.20190702.13,
  author = {Yapin Li and Huisuo Yang and Haiyang Zhang and Min Wang and Qingfeng Li and Jian Wang and Wenjing Song and Dongqi Gao},
  title = {An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus GII Infection in a University},
  journal = {Science Discovery},
  volume = {7},
  number = {2},
  pages = {72-77},
  doi = {10.11648/j.sd.20190702.13},
  url = {https://doi.org/10.11648/j.sd.20190702.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20190702.13},
  abstract = {Objective: To investigate an acute gastroenteritis epidemic in a university and to identify the scale, to find the possible causes of the outbreak. Methods: The field epidemiological survey method was used for information collection. Case-control and retrospective cohort study methods were used. The database was established with SPSS 25.0 and statistical analysis was performed. Results: In January 2018, an outbreak of acute gastroenteritis occurred in a university. A total of 162 cases were found and the attack rate was 8.94% (162/1813), all of whom were students. All the cases were eaten in the same student canteen. Case-control studies showed that on January 10th, lunch braised pork ribs, 10th dinner tomato scrambled eggs, and 11th dinner cakes were suspicious food. Norovirus nucleic acid was detected in the anal swab and fecal specimens of the case and canteen staff, all of which were GII type. The investigation found that there was no hand washing facility in the student canteen. The staff in the canteen did not wear masks, hats and gloves in the operation. The kitchen had no tableware disinfection cabinet, and the canteen detected 4 cases of Norovirus nucleic acid positive. Conclusions: This epidemic was an outbreak of acute gastroenteritis caused by Norovirus GII infection in a university. It is recommended to strengthen the management of food workers, strictly check the medical examination before taking up the post, strictly apply the fake sales system, and regularly check the personnel who have symptoms related to the gastrointestinal tract. Purchase food cabinet disinfection cabinets, disinfect food utensils in strict accordance with the operating procedures; add hand washing facilities in the cafeteria; change the table meal method into a meal method. Conduct health education for students and develop good health habits.},
 year = {2019}
}

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